Article
Evolution of duplicated IgH loci in Atlantic salmon, Salmo salar.
BMC genomics - 2 Sept 2010
Yasuike Motoshige, de Boer Johan, von Schalburg Kristian R, Cooper Glenn A, McKinnel Linda, Messmer Amber, So Stacy, Davidson William S, Koop Ben F
Abstract excerpt
BACKGROUND: The Atlantic salmon (Salmo salar) immunoglobulin heavy chain (IgH) locus possesses two parallel IgH isoloci (IGH-A and IGH-B), that are related to the genomic duplication event in the family Salmonidae. These duplicated IgH loci in Atlantic salmon provide a unique opportunity to examine the mechanisms of genome diversity and genome evolution of the IgH loci in vertebrates. In this study, we defined...
Topics
- Animals
- Atlantic Ocean
- Evolution, Molecular
- Gene Duplication
- Gene Expression Profiling
- Gene Expression Regulation, Developmental
- Gene Rearrangement, B-Lymphocyte, Heavy Chain
- Genes, Immunoglobulin Heavy Chain
- Genetic Loci
- Genetic Variation
- Immunoglobulin Constant Regions
- Immunoglobulin Variable Region