Article
Distinct patterns of IgH structure and organization in a divergent lineage of chrondrichthyan fishes.
Immunogenetics - 1 Jan 1998
Rast J P, Amemiya C T, Litman R T, Strong S J, Litman G W
Abstract excerpt
Immunoglobulin heavy chain (IgH) genes in representative chondrichthyan fishes (sharks and skates) consist of independently functioning clusters, containing separate variable (VH), diversity (DH), and joining (JH) region elements and constant (CH) region exons. IgH loci have been characterized in...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Southern
- DNA, Complementary
- Dogfish
- Electrophoresis, Gel, Pulsed-Field
- Gene Library
- Genetic Linkage
- Genetic Variation
- Immunoglobulin Fragments
- Immunoglobulin Heavy Chains
- Immunoglobulin Joining Region
- Immunoglobulin Variable Region
- Molecular Sequence Data
- Multigene Family
- Pseudogenes
- Sequence Homology, Amino Acid
