Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interconnected subsets of memory follicular helper T cells have different effector functions.

Nature communications - 10 Oct 2017

Asrir Assia, Aloulou Meryem, Gador Mylène, Pérals Corine, Fazilleau Nicolas

Abstract excerpt

Follicular helper T cells regulate high-affinity antibody production. Memory follicular helper T cells can be local in draining lymphoid organs and circulate in the blood, but the underlying mechanisms of this subdivision are unresolved. Here we show that both memory follicular helper T subsets sustain B-cell responses after reactivation. Local cells promote more plasma cell differentiation, whereas circulating...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immunologic Memory
Share to Lymph Nodes
Share to Mice, Inbred C57BL

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Transgenic

Share to Phenotype

Share to Spleen

Share to T-Lymphocytes, Helper-Inducer

Source

Open in PubMed Open full text

Identifiers

PMID: 29018187
DOI: 10.1038/s41467-017-00843-7
PMCID: PMC5635037

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interconnected subsets of memory follicular helper T cells have different effector functions.PMID 29018187Read ↗

Here, there and everywhere: T follicular helper cells on the move.Semantic proximity Read ↗

Biology and clinical relevance of follicular cytotoxic T cellsSemantic proximity Read ↗

The elusive identity of T follicular helper cells.Semantic proximity Read ↗

A novel memory-like Tfh cell subset is precursor to effector Tfh cells in recall immune responses.Semantic proximity Read ↗

Tissue-resident memory T cells.Semantic proximity Read ↗

CD4+CD8+ T follicular helper cells regulate humoral immunity in chronic inflammatory lesionsSemantic proximity Read ↗

Axes of heterogeneity in human tissue-resident memory T cells.Semantic proximity Read ↗

Circulating CXCR5+CD4+helper T cells in systemic lupus erythematosus patients share phenotypic properties with germinal center follicular helper T cells and promote antibody production.Semantic proximity Read ↗

Transcriptional and epigenetic regulation of follicular T-helper cells and their role in autoimmunitySemantic proximity Read ↗

Follicular helper T cells expressing Blimp1 are specialized for plasma cell differentiationSemantic proximity Read ↗

Memory B cells: effectors of long-lived immune responses.Semantic proximity Read ↗

A dynamic activation–memory cycle organizes the human IgG⁺ memory B cell compartmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.