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Article

T follicular helper cells in germinal center B cell selection and lymphomagenesis.

Immunological reviews - 1 Jul 2020

Mintz Michelle A, Cyster Jason G

Abstract excerpt

Germinal centers (GCs) are confined anatomic regions where rapidly proliferating B cells undergo somatic mutation and selection and eventual differentiation into memory B cells or long-lived plasma cells. GCs are also the origin of malignancy, namely follicular lymphoma (FL), GC B cell-diffuse large B cell lymphoma (GCB-DLBCL), and Burkitt lymphoma (BL). GC B cell lymphomas maintain their GC transcriptional...

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Identifiers

PMID: 32412663
DOI: 10.1111/imr.12860
PMCID: PMC7817257

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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