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Article

The cytoplasmic location of chicken mx is not the determining factor for its lack of antiviral activity.

PloS one - 16 Aug 2010

Benfield Camilla T O, Lyall Jon W, Tiley Laurence S

Abstract excerpt

BACKGROUND: Chicken Mx belongs to the Mx family of interferon-induced dynamin-like GTPases, which in some species possess potent antiviral properties. Conflicting data exist for the antiviral capability of chicken Mx. Reports of anti-influenza activity of alleles encoding an Asn631 polymorphism have not been supported by subsequent studies. The normal cytoplasmic localisation of chicken Mx may influence its...

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Identifiers

PMID: 20808435
DOI: 10.1371/journal.pone.0012151
PMCID: PMC2922328

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Source receipt: pubmed, retrieved 7 Sept 2026.

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