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Article

Mx is dispensable for interferon-mediated resistance of chicken cells against influenza A virus.

Journal of virology - 1 Aug 2011

Schusser Benjamin, Reuter Antje, von der Malsburg Alexander, Penski Nicola, Weigend Steffen, Kaspers Bernd, Staeheli Peter, Härtle Sonja

Abstract excerpt

The type I interferon (IFN) system plays an important role in antiviral defense against influenza A viruses (FLUAV), which are natural chicken pathogens. Studies of mice identified the Mx1 protein as a key effector molecule of the IFN-induced antiviral state against FLUAV. Chicken Mx genes are highly polymorphic, and recent studies suggested that an Asn/Ser polymorphism at amino acid position 631 determines the...

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Identifiers

PMID: 21632756
DOI: 10.1128/JVI.00535-11
PMCID: PMC3147972

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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