Article
Avian cells expressing the murine Mx1 protein are resistant to influenza virus infection.
Virology - 1 Feb 1991
Garber E A, Chute H T, Condra J H, Gotlib L, Colonno R J, Smith R G
Abstract excerpt
The cDNA encoding the murine Mx1 protein, a mediator of resistance to influenza virus, was inserted into a replication-competent avian retroviral vector in either the sense (referred to as Mx+) or the antisense (referred to as Mx-) orientation relative to the viral structural genes. Both vectors produced virus retaining the Mx insert (Mx recombinant viruses referred to as Mx+ and Mx-) following transfection into...
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