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Article

Genetic variants within the MAP kinase signalling network and anti-TNF treatment response in rheumatoid arthritis patients.

Annals of the rheumatic diseases - 1 Jan 2011

Coulthard Lydia R, Taylor John C, Eyre Steve, Robinson James I, Wilson Anthony G, Isaacs John D, Hyrich Kimme, Emery Paul, Barton Anne, Barrett Jennifer H, Morgan Ann W, McDermott Michael F

Abstract excerpt

BACKGROUND: Rheumatoid arthritis (RA) does not always respond to available treatments, including tumour necrosis factor (TNF) antagonists. A study was undertaken to investigate whether genetic variation within genes, encoding proteins in the p38 signalling network, contributes to the variable res...

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Share to Adalimumab
Share to Antibodies, Monoclonal, Humanized

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to p38 Mitogen-Activated Protein Kinases

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Source

Identifiers

PMID: 20805296
DOI: 10.1136/ard.2010.133249

Genes

TNF
MAPK14
MAPKAPK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20805296-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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