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Article

Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury.

Journal of hepatology - 1 Dec 2010

Donaldson Peter T, Daly Ann K, Henderson Jill, Graham Julia, Pirmohamed Munir, Bernal William, Day Christopher P, Aithal Guruprasad P

Abstract excerpt

BACKGROUND & AIMS: Co-amoxiclav is one of the most common causes of drug-induced liver injury (DILI). Although there are previous reports of genetic associations between HLA class II and co-amoxiclav-related DILI, studies to date have been based on very small numbers from single centres only. In order to address this problem we have investigated the role of HLA class II DRB1 and DQB1 in 61 cases of co-amoxiclav...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20800921
DOI: 10.1016/j.jhep.2010.05.033

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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