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Article

Activation of Notch signaling in cardiomyocytes during post-infarction remodeling

30 Aug 2010

Abstract excerpt

OBJECTIVE: Notch signaling is crucial for cell-to-cell interaction during cardiovascular development and may influence differentiation, proliferation, and apoptotic events. We investigated whether Notch signaling is activated during myocardial remodeling in heart failure (HF). DESIGN: Myocardial gene expression and localization of Notch receptors (Notch1-4) and ligands (Jagged1-2, and Delta-like (Dll)-1 and 4)...

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Share to Developmental Biology and Gene Regulation
Share to Cardiac Fibrosis and Remodeling
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Identifiers

PMID: 20799913
DOI: 10.3109/14017431.2010.511256

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