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Article

Notch signalling in ventricular chamber development and cardiomyopathy

4 Jun 2016

Abstract excerpt

The vertebrate heart is the first organ to form and function during embryogenesis. Primitive streak-derived cardiac progenitors located bilaterally move rostral to form the primitive heart tube that subsequently undergoes rightward looping, remodelling and septation to give rise to the mature four-chambered heart. Tightly regulated tissue interactions orchestrate the patterning, proliferation and differentiation...

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PMID: 27260948
DOI: 10.1111/febs.13773

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