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BMP7 promotes cardiomyocyte regeneration in zebrafish and adult mice

27 Apr 2024

Abstract excerpt

Zebrafish have a lifelong cardiac regenerative ability after damage, whereas mammals lose this capacity during early postnatal development. This study investigated whether the declining expression of growth factors during postnatal mammalian development contributes to the decrease of cardiomyocyte regenerative potential. Besides confirming the proliferative ability of neuregulin 1 (NRG1), interleukin (IL)1b,...

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PMID: 38678558
DOI: 10.1016/j.celrep.2024.114162

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