Article
Mouse strain variation in maximal electroshock seizure threshold.
Brain research - 17 May 2002
Ferraro Thomas N, Golden Gregory T, Smith George G, DeMuth Denis, Buono Russell J, Berrettini Wade H
Abstract excerpt
Maximal electroshock seizure threshold (MEST) is a classical measure of seizure sensitivity with a wide range of experimental applications. We determined MEST in nine inbred mouse strains and one congenic strain using a procedure in which mice are given one shock per day with an incremental (1 mA) current increase in each successive trial until a maximal seizure (tonic hindlimb extension) is elicited. C57BL/6J...
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