Article
Expression of the HTLV-I tax transactivator in yeast: correlation between phenotypic alterations and tax function in higher eukaryotes.
AIDS research and human retroviruses - 1 Nov 1990
Kramer R A, Tomchak L, Ruben S M, Rosen C A
Abstract excerpt
The transcriptional activator protein (Tax) from human T-cell leukemia virus type 1 was expressed in yeast using several different promoters in several strains: In all instances, expression of Tax resulted in very strong aggregation of the yeast cells. This phenotype appears to be identical by all criteria tested to the flocculation phenotype of the dominant mutation flo 1. Of most significance, mutations in Tax...
Topics
- Gene Products, tax
- Human T-lymphotropic virus 1
- Immunoblotting
- Mutation
- Phenotype
- Promoter Regions, Genetic
- Saccharomyces cerevisiae
- Transcriptional Activation