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Article

Protein misfolding induces hypoxic preconditioning via a subset of the unfolded protein response machinery.

Molecular and cellular biology - 1 Nov 2010

Mao Xianrong R, Crowder C Michael

Abstract excerpt

Prolonged cellular hypoxia results in energy failure and ultimately cell death. However, less-severe hypoxia can induce a cytoprotective response termed hypoxic preconditioning (HP). The unfolded protein response pathway (UPR) has been known for some time to respond to hypoxia and regulate hypoxi...

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Identifiers

PMID: 20733002
DOI: 10.1128/MCB.00922-10
PMCID: PMC2953055

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20733002-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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