Article
Autophagy protects against hypoxic injury in C. elegans.
Autophagy - 1 Nov 2008
Samokhvalov Victor, Scott Barbara A, Crowder C Michael
Abstract excerpt
Macroautophagy has been implicated in a variety of pathological processes. Hypoxic/ischemic cellular injury is one such process in which autophagy has emerged as an important regulator. In general, autophagy is induced after a hypoxic/ischemic insult; however, whether the induction of autophagy promotes cell death or recovery is controversial and appears to be context dependent. We have developed C. elegans as a...
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