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Article

Partially active HIV-1 Vif alleles facilitate viral escape from specific antiretrovirals.

AIDS (London, England) - 24 Sept 2010

Fourati Slim, Malet Isabelle, Binka Mawuena, Boukobza Stephanie, Wirden Marc, Sayon Sophie, Simon Anne, Katlama Christine, Simon Viviana, Calvez Vincent, Marcelin Anne-Geneviève

Abstract excerpt

BACKGROUND: The HIV-1 Vif protein counteracts the antiviral activity of the cytidine deaminases APOBEC3G and APOBEC3F. Natural variation in Vif may result in reduced efficacy against APOBEC3 proteins and in increased HIV-1 diversity. We speculated that this mechanism could facilitate viral escape...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20729708
DOI: 10.1097/QAD.0b013e32833e515a

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20729708-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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