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[Prevalence status and mutation pattern of H221Y in subtype B' of HIV-1].

Zhonghua yi xue za zhi - 31 Jan 2012

Li Han-ping, Guo Wei, Liu Yong-jian, Bao Zuo-yi, Li Lin, Zhuang Dao-min, Liu Si-yang, Wang Xiao-lin, Li Jing-yun

Abstract excerpt

OBJECTIVE: To explore the prevalence and mutation pattern of H221Y at reverse transcriptase (RT) among the subtype B' of human immunodeficiency virus1 (HIV-1) in antiviral therapy-failure patients. METHODS: A total of 1363 sequences, comprising of 1205 therapy-failure individuals and 158 therapy-naive individuals, were submitted to the Stanford HIV drug resistance database (SHDB) to analyze the frequency and...

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PMID: 22490797

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