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Article

Long-term restriction by APOBEC3F selects human immunodeficiency virus type 1 variants with restored Vif function.

Journal of virology - 1 Oct 2010

Albin John S, Haché Guylaine, Hultquist Judd F, Brown William L, Harris Reuben S

Abstract excerpt

Tandem stop mutations K26X and H27X in human immunodeficiency virus type 1 (HIV-1) vif compromise virus replication in human T-cell lines that stably express APOBEC3F (A3F) or APOBEC3G (A3G). We previously reported that partial resistance to A3G could develop in these Vif-deficient viruses through a nucleotide A200-to-T/C transversion and a vpr null mutation, but these isolates were still susceptible to...

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Source

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Identifiers

PMID: 20686027
DOI: 10.1128/JVI.00632-10
PMCID: PMC2937771

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Long-term restriction by APOBEC3F selects human immunodeficiency virus type 1 variants with restored Vif function.PMID 20686027Read ↗

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