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Article

Acinus: a nuclear regulator of autophagy and endocytic trafficking.

Autophagy - 1 Oct 2010

Krämer Helmut

Abstract excerpt

Fusion with lysosomes is the common last step of endocytic trafficking and autophagy. Accordingly, several proteins are required in both pathways for cargoes to reach their destinations. Among these proteins, Drosophila Acinus stands out, as it exerts opposite effects on these two pathways, and thus establishes a new paradigm. Loss of Acinus function destabilizes early endosomes, thereby promoting the delivery of...

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Identifiers

PMID: 20729631
DOI: 10.4161/auto.6.7.13100
PMCID: PMC3039744

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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