Article
Rapid identification of JAK2 exon 12 mutations using high resolution melting analysis.
Haematologica - 1 Oct 2008
Jones Amy V, Cross Nicholas C P, White Helen E, Green Anthony R, Scott Linda M
Abstract excerpt
Diverse JAK2 exon 12 mutations have been described in patients with V617F-negative polycythemia vera. Development of a sensitive detection assay capable of identifying any of these mutations is required for medium-throughput diagnostic screens. Non-mutated and mutant JAK2 exon 12 alleles were amp...
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