Article
Whole brain and regional hyperintense white matter volume and blood pressure: overlap of genetic loci produced by bivariate, whole-genome linkage analyses.
Stroke - 1 Oct 2010
Kochunov Peter, Glahn David, Lancaster Jack, Winkler Anderson, Kent Jack W, Olvera Rene L, Cole Shelley A, Dyer Thomas D, Almasy Laura, Duggirala Ravi, Fox Peter T, Blangero John
Abstract excerpt
BACKGROUND AND PURPOSE: The volume of T2-hyperintense white matter (HWM) is an important neuroimaging marker of cerebral integrity with a demonstrated high heritability. Pathophysiology studies have shown that the regional, ependymal, and subcortical HWM lesions are associated with elevated arter...
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