Article
Carotid intima-media thickness (cIMT) cosegregates with blood pressure and renal function in hypertensive Hispanic families.
Atherosclerosis - 1 May 2008
Chen Yi-Chun, Guo Xiuqing, Raffel Leslie J, Xiang Anny H, Fang Belle, Hsueh Willa A, Taylor Kent D, Buchanan Thomas A, Hodis Howard N, Rotter Jerome I
Abstract excerpt
BACKGROUND: Carotid intima-media thickness (cIMT) is commonly used as a surrogate for atherosclerosis. Since cIMT is correlated with hypertension and microalbuminuria, we tested the hypothesis that there is a genetic basis for the observed relationship between cIMT, blood pressure (BP), and renal function within high risk families. METHODS: Six hundred and three nondiabetic individuals from 149 Hispanic American...
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