Article
Genome-wide linkage screen for systolic blood pressure in the Veterans Administration Genetic Epidemiology Study (VAGES) of Mexican-Americans and confirmation of a major susceptibility locus on chromosome 6q14.1.
Human heredity - 1 Jan 2011
Puppala Sobha, Coletta Dawn K, Schneider Jennifer, Hu Shirley L, Farook Vidya S, Dyer Thomas D, Arya Rector, Blangero John, Duggirala Ravindranath, DeFronzo Ralph A, Jenkinson Christopher P
Abstract excerpt
OBJECTIVE: Hypertension or high blood pressure is a strong correlate of diseases such as obesity and type 2 diabetes. We conducted a genome-wide linkage screen to identify susceptibility genes influencing systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Mexican-Americans from the Veterans Administration Genetic Epidemiology Study (VAGES). METHODS: Using data from 1,089 individuals distributed...
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