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Article

Genome-Wide Linkage Analysis for Loci Affecting Pulse Pressure

14 Nov 2005

Abstract excerpt

Pulse pressure, the difference between systolic and diastolic blood pressure, is an independent risk factor for cardiovascular disease. Increased pulse pressure reflects reduced compliance of arteries and is a marker of atherosclerosis. To locate genes that affect pulse pressure, a genome-wide linkage scan for quantitative trait loci influencing pulse pressure was performed using variance components methods as...

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PMID: 16286574
DOI: 10.1161/01.hyp.0000191706.41980.29

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