Article
A whole genome scan for pulse pressure/stroke volume ratio in African Americans: the HyperGEN study.
American journal of hypertension - 1 Apr 2007
Sherva Richard, Miller Michael B, Lynch Amy I, Devereux Richard B, Rao D C, Oberman Albert, Hopkins Paul N, Kitzman Dalane W, Atwood Larry D, Arnett Donna K
Abstract excerpt
BACKGROUND: Arterial stiffness is reported in numerous family studies to be heritable. Linkage analysis has identified genomic regions that likely harbor genes contributing to its phenotypic expression. We sought to identify loci contributing to arterial stiffness in a large group of African-American hypertensive families. METHODS: We performed a genome scan on 1251 African Americans in families participating in...
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