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Article

Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility.

Annals of the rheumatic diseases - 1 Jan 2011

Meulenbelt Ingrid, Bos Steffan D, Chapman Kay, van der Breggen Ruud, Houwing-Duistermaat Jeanine J, Kremer Dennis, Kloppenburg Margreet, Carr Andrew, Tsezou Aspasia, González Antonio, Loughlin John, Slagboom P Eline

Abstract excerpt

OBJECTIVE: To study whether common genetic variants of the genes involved in the complex regulatory mechanism determining the intracellular bio-availability of T3 influence osteoarthritis onset. METHODS: In total 17 genetic variants within the genes encoding WD40-repeat/SOCS-box protein 1, ubiqui...

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Source

Identifiers

PMID: 20724312
DOI: 10.1136/ard.2010.133660

Genes

DIO3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20724312-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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