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Article

Genetic predisposition to thyrotoxicosis and onset of knee osteoarthritis.

Frontiers in endocrinology - 1 Jan 2024

He Zhiyi, Gong Zailing, Jiao Sizhe, Xiong Wei, Hao Xiaoxia, Cui Jiarui, Zhang Jiaming

Abstract excerpt

Objective: Thyroid hormones have actions on cartilage, whereas the association between thyroid hormone related diseases and osteoarthritis (OA) are unclear. This study aims to investigate the association between thyrotoxicosis and OA. Methods: Summary-level genetic data of thyrotoxicosis were obtained from FinnGen cohorts (nCase = 10,569, nControl = 762,037). Summary-level data of OA were obtained from a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39415792
DOI: 10.3389/fendo.2024.1364027
PMCID: PMC11479908

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