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Article

MC1R genotype may modify the effect of sun exposure on melanoma risk in the GEM study.

Cancer causes & control : CCC - 1 Dec 2010

Kricker Anne, Armstrong Bruce K, Goumas Chris, Kanetsky Peter, Gallagher Richard P, Begg Colin B, Millikan Robert C, Dwyer Terence, Rosso Stefano, Marrett Loraine D, Thomas Nancy E, Berwick Marianne

Abstract excerpt

We investigated whether MC1R genotype modifies the effect of sun exposure on melanoma risk in 1,018 cases with multiple melanomas (MPM) and 1,875 controls with one melanoma (SPM). There was some suggestion that MC1R genotype modified the effect of beach and water activities on MPM risk: ORs were 1.94 (95% CI 1.40-2.70) for any activities for no R variants and 1.39 (95% CI 1.05-1.84) with R variants (R151C, R160W,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Head and Neck Neoplasms

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Share to Receptor, Melanocortin, Type 1

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Source

Open in PubMed Open full text

Identifiers

PMID: 20721616
DOI: 10.1007/s10552-010-9633-3
PMCID: PMC3010306

Genes

GEM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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