Article
Pooled versus individual genotyping in a breast cancer genome-wide association study.
Genetic epidemiology - 1 Sept 2010
Huang Ying, Hinds David A, Qi Lihong, Prentice Ross L
Abstract excerpt
We examine the measurement properties of pooled DNA odds ratio estimates for 7,357 single nucleotide polymorphisms (SNPs) genotyped in a genome-wide association study of postmenopausal breast cancer. This study involved DNA pools formed from 125 cases or 125 matched controls. Individual genotyping for these SNPs subsequently came available for a substantial majority of women included in seven pool pairs,...
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