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Article

Integrin-Mediated Cell-Matrix Interaction in Physiological and Pathological Blood Vessel Formation

18 Sept 2011

Abstract excerpt

Physiological as well as pathological blood vessel formation are fundamentally dependent on cell-matrix interaction. Integrins, a family of major cell adhesion receptors, play a pivotal role in development, maintenance, and remodeling of the vasculature. Cell migration, invasion, and remodeling of the extracellular matrix (ECM) are integrin-regulated processes, and the expression of certain integrins also...

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PMID: 21941547
DOI: 10.1155/2012/125278

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