Biological functions of maspin

Abstract excerpt

Maspin (Mammary Serine Protease Inhibitor) was first reported in 1994 as a serpin with tumor suppressive properties. Maspin was initially isolated through subtractive hybridization and differential display analysis as a 42-kDa protein that is expressed in normal mammary epithelial cells but reduced or absent in breast carcinomas (Zou et al., 1994). Further research led to maspin's characterization as a class II...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Advanced Proteomics Techniques and Applications
• Share to Bone and Dental Protein Studies
• Share to Protease and Inhibitor Mechanisms