maspin suppresses the invasive phenotype of human breast carcinoma.

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Article

maspin suppresses the invasive phenotype of human breast carcinoma.

Cancer research - 15 Dec 1998

Seftor R E, Seftor E A, Sheng S, Pemberton P A, Sager R, Hendrix M J

Abstract excerpt

The recently discovered tumor suppressor gene maspin has been shown to inhibit tumor cell motility, invasion, and metastasis in breast cancer by our laboratories. Nonetheless, the exploitation of maspin as a potential diagnostic and/or therapeutic tool has remained limited due to the lack of know...

Topics

Antibodies, Blocking
Antineoplastic Agents
Breast Neoplasms
Cell Adhesion
Cell Survival
Genes, Tumor Suppressor
Humans
Integrins
Neoplasm Invasiveness
Phenotype
Proteins
Receptors, Fibronectin
Recombinant Proteins
Serpins
Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 9865722

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9865722-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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