Article
maspin suppresses the invasive phenotype of human breast carcinoma.
Cancer research - 15 Dec 1998
Seftor R E, Seftor E A, Sheng S, Pemberton P A, Sager R, Hendrix M J
Abstract excerpt
The recently discovered tumor suppressor gene maspin has been shown to inhibit tumor cell motility, invasion, and metastasis in breast cancer by our laboratories. Nonetheless, the exploitation of maspin as a potential diagnostic and/or therapeutic tool has remained limited due to the lack of knowledge concerning its molecular and biological mechanism(s) of action. The work reported here demonstrates that...
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