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Article

Distribution of acetyltransferase activities in the intestines of rapid and slow acetylator rabbits.

Carcinogenesis - 1 Aug 1991

Ilett K F, Reeves P T, Minchin R F, Kinnear B F, Watson H F, Kadlubar F F

Abstract excerpt

Epidemiological studies have shown that there is a significantly greater proportion of the rapid acetylator phenotype in patients with colorectal tumors than in controls; phenotype-related differences in bioactivation of dietary or environmental amines in the intestinal epithelium have been suggested as a mechanism for this effect. In the present study, we have used hepatic and intestinal cytosols to compare...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 1860167
DOI: 10.1093/carcin/12.8.1465

Genes

NAT2
OAT
NAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Distribution of acetyltransferase activities in the intestines of rapid and slow acetylator rabbits.PMID 1860167Read ↗

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Rabbit N-acetyltransferase 2 genotyping method to investigate role of acetylation polymorphism on N- and O-acetylation of aromatic and heterocyclic amine carcinogens.Semantic proximity Read ↗

Distribution of 2-aminofluorene and p-aminobenzoic acid N-acetyltransferase activity in tissues of C57BL/6J rapid and B6.A-NatS slow acetylator congenic mice.Semantic proximity Read ↗

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