Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hypothalamic-pituitary-adrenal axis functioning in Huntington's disease mutation carriers compared with mutation-negative first-degree controls.

Brain research bulletin - 30 Oct 2010

van Duijn Erik, Selis Mischa A, Giltay Erik J, Zitman Frans G, Roos Raymund A C, van Pelt Hans, van der Mast Rose C

Abstract excerpt

Neurodegeneration in Huntington's disease (HD) occurs in various brain regions including the hypothalamus. In this cross-sectional study, hypothalamic-pituitary-adrenal (HPA) axis functioning was studied in 26 presymptomatic and 58 symptomatic HD mutation carriers, and 28 controls. HPA axis functioning was measured through salivary cortisol in the day curve, the cortisol awakening response (CAR), the area under...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Circadian Rhythm
Share to Huntingtin Protein

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Huntington Disease

Share to Hydrocortisone

Share to Hypothalamo-Hypophyseal System

Share to Nerve Tissue Proteins

Share to Pituitary-Adrenal System

Share to Saliva

Source

Identifiers

PMID: 20713132
DOI: 10.1016/j.brainresbull.2010.08.006

Genes

DST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hypothalamic-pituitary-adrenal axis functioning in Huntington's disease mutation carriers compared with mutation-negative first-degree controls.PMID 20713132Read ↗

Hypothalamic-pituitary-adrenal axis functioning in Huntington's disease and its association with depressive symptoms and suicidality.Semantic proximity Read ↗

Urinary cortisol level in exclusion autonomous cortisol secretion in the patient of primary aldosteronismSemantic proximity Read ↗

HPA axis dysregulation associated to apolipoprotein E4 genotype in Alzheimer's disease.Semantic proximity Read ↗

The cortisol awakening response in bipolar illness: a pilot study.Semantic proximity Read ↗

Brain serotonin 4 receptor binding is associated with the cortisol awakening response.Semantic proximity Read ↗

Corticosterone dysregulation exacerbates disease progression in the R6/2 transgenic mouse model of Huntington's disease.Semantic proximity Read ↗

Understanding corticosterone fluctuations and HPA-axis regulation in a mouse model of Spinocerebellar ataxia type 3Semantic proximity Read ↗

Neuroendocrine evidence of normal hypothalamus-pituitary dopaminergic function in Huntington's disease.Semantic proximity Read ↗

Dissimilar Changes in Serum Cortisol after Epileptic and Psychogenic Non-Epileptic Seizures: A Promising Biomarker in the Differential Diagnosis of Paroxysmal Events?Semantic proximity Read ↗

Effects of acute metabolic stress on the dopaminergic and pituitary-adrenal axis activity in patients with schizophrenia, their unaffected siblings and controls.Semantic proximity Read ↗

Cortisol response patterns in depressed women and their healthy daughters at risk: Comparison with healthy women and their daughters.Semantic proximity Read ↗

C3435T polymorphism of the MDR1 gene is not associated with blood levels of hypothalamus-pituitary-adrenal axis hormones in healthy male subjects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.