Article
Effects of acute metabolic stress on the dopaminergic and pituitary-adrenal axis activity in patients with schizophrenia, their unaffected siblings and controls.
Schizophrenia research - 1 Mar 2008
Brunelin Jerome, d'Amato Thierry, van Os Jim, Cochet Alain, Suaud-Chagny Marie-Françoise, Saoud Mohamed
Abstract excerpt
A genetically mediated abnormal sensitivity to stress is thought to play a role in the onset, exacerbation and relapse of schizophrenia. In a double blind, placebo-controlled crossover study, peak increases in plasma ACTH (Delta ACTH) and homovanillic-acid, a dopamine metabolite, (Delta HVA) foll...
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