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Article

Hypothalamic-pituitary-adrenal axis functioning in Huntington's disease and its association with depressive symptoms and suicidality.

Journal of neuroendocrinology - 1 Mar 2015

Hubers A A M, van der Mast R C, Pereira A M, Roos R A C, Veen L J, Cobbaert C M, van Duijn E, Giltay E J

Abstract excerpt

Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis has been reported in Huntington's disease (HD). In non-HD populations, alterations in HPA axis activity have been associated with depression and suicidality. The present study aims to compare HPA axis activity between HD mutation carr...

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Identifiers

PMID: 25565388
DOI: 10.1111/jne.12255

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25565388-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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