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Article

DNA methylation changes in ex-adenoma carcinoma of the large intestine.

Virchows Archiv : an international journal of pathology - 1 Oct 2010

Kwon Hyeong-Ju, Kim Jung Ho, Bae Jeong Mo, Cho Nam-Yun, Kim Tae-You, Kang Gyeong Hoon

Abstract excerpt

Ex-adenoma carcinoma (EAC) is a carcinoma with contiguous adenoma element in its vicinity which provides a morphological evidence for adenoma-carcinoma sequence. During multistep colorectal carcinogenesis, promoter CpG island hypermethylation has been known to increase in a stepwise manner whereas diffuse genomic hypomethylation has been known to be an early event and not progress. However, some controversies...

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PMID: 20711609
DOI: 10.1007/s00428-010-0958-9

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SAT2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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