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Article

Hypermethylated MAL gene – a silent marker of early colon tumorigenesis

17 Mar 2008

Abstract excerpt

BACKGROUND: Tumor-derived aberrantly methylated DNA might serve as diagnostic biomarkers for cancer, but so far, few such markers have been identified. The aim of the present study was to investigate the potential of the MAL (T-cell differentiation protein) gene as an early epigenetic diagnostic marker for colorectal tumors. METHODS: Using methylation-specific polymerase chain reaction (MSP) the promoter...

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Share to Cancer-related gene regulation
Share to Epigenetics and DNA Methylation
Share to Genetic factors in colorectal cancer

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PMID: 18346269
DOI: 10.1186/1479-5876-6-13

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