sli-3 negatively regulates the LET-23/epidermal growth factor receptor-mediated vulval induction pathway in Caenorhabditis elegans.

doi:10.1534/genetics.106.063990

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Article

sli-3 negatively regulates the LET-23/epidermal growth factor receptor-mediated vulval induction pathway in Caenorhabditis elegans.

Genetics - 1 Nov 2006

Gupta Bhagwati P, Liu Jing, Hwang Byung J, Moghal Nadeem, Sternberg Paul W

Abstract excerpt

The LIN-3-LET-23-mediated inductive signaling pathway plays a major role during vulval development in C. elegans. Studies on the components of this pathway have revealed positive as well as negative regulators that function to modulate the strength and specificity of the signal transduction casca...

Topics

Alleles
Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Cell Lineage
Chromosome Mapping
Embryo, Nonmammalian
Embryonic Induction
Epistasis, Genetic
ErbB Receptors
Ethyl Methanesulfonate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Female

Gene Expression Regulation, Developmental

Genes, Helminth

Genetic Markers

Helminth Proteins

Mutagenesis

Mutagens

Source

Open in PubMed Open full text

Identifiers

PMID: 16980384
DOI: 10.1534/genetics.106.063990
PMCID: PMC1667086

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-16980384-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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sli-3 negatively regulates the LET-23/epidermal growth factor receptor-mediated vulval induction pathway in Caenorhabditis elegans.PMID 16980384Read ↗

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