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Article

sli-3 negatively regulates the LET-23/epidermal growth factor receptor-mediated vulval induction pathway in Caenorhabditis elegans.

Genetics - 1 Nov 2006

Gupta Bhagwati P, Liu Jing, Hwang Byung J, Moghal Nadeem, Sternberg Paul W

Abstract excerpt

The LIN-3-LET-23-mediated inductive signaling pathway plays a major role during vulval development in C. elegans. Studies on the components of this pathway have revealed positive as well as negative regulators that function to modulate the strength and specificity of the signal transduction cascade. We have carried out genetic screens to identify new regulators of this pathway by screening for suppressors of...

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Identifiers

PMID: 16980384
DOI: 10.1534/genetics.106.063990
PMCID: PMC1667086

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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