Article
Mutations in the Caenorhabditis elegans let-23 EGFR-like gene define elements important for cell-type specificity and function.
The EMBO journal - 15 Jan 1994
Aroian R V, Lesa G M, Sternberg P W
Abstract excerpt
The Caenorhabditis elegans let-23 gene is a genetically characterized member of the epidermal growth factor receptor (EGFR) tyrosine kinase family. Mutations in let-23 can produce five phenotypes in the nematode. Alleles of let-23 include null alleles, reduction-of-function alleles and alleles that disrupt function in some cell types and not others. We have sequenced some of these mutations to identify sequences...
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