Article
Genetic variants in matrix metalloproteinase-9 gene modify metalloproteinase-9 levels in black subjects.
DNA and cell biology - 1 Apr 2012
Metzger Ingrid F, Luizon Marcelo R, Lacchini Riccardo, Tanus-Santos Jose Eduardo
Abstract excerpt
Altered matrix metalloproteinases (MMPs) levels are involved in cardiovascular diseases and increased MMP-9 levels enhance the cardiovascular risk in apparently healthy subjects. We investigated the effects of MMP-9 gene polymorphisms and haplotypes on the circulating MMP-9 levels in healthy black subjects and the effects of an MMP-2 polymorphism on the plasma MMP-2 concentrations. We studied 190 healthy...
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