Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Eco1 is important for DNA damage repair in S. cerevisiae.

Cell cycle (Georgetown, Tex.) - 15 Aug 2010

Lu Shuai, Goering Matthew, Gard Scarlett, Xiong Bo, McNairn Adrian J, Jaspersen Sue L, Gerton Jennifer L

Abstract excerpt

The cohesin network has an essential role in chromosome segregation, but also plays a role in DNA damage repair. Eco1 is an acetyltransferase that targets subunits of the cohesin complex and is involved in both the chromosome segregation and DNA damage repair roles of the network. Using budding yeast as a model system, we find that mutations in Eco1, including a genocopy of a human Roberts syndrome allele, do not...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetyltransferases
Share to Antibiotics, Antineoplastic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Bleomycin

Share to Checkpoint Kinase 2

Share to Chromosome Segregation

Share to Cohesins

Share to DNA Breaks, Double-Stranded

Share to X-Rays

Source

Open in PubMed Open full text

Identifiers

PMID: 20703090
DOI: 10.4161/cc.9.16.12673
PMCID: PMC3230479

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Eco1 is important for DNA damage repair in S. cerevisiae.PMID 20703090Read ↗

The cohesin acetyltransferase Eco1 coordinates rDNA replication and transcription.Semantic proximity Read ↗

Eco1-dependent cohesin acetylation during establishment of sister chromatid cohesion.Semantic proximity Read ↗

Fdo1, Fkh1, Fkh2 and the Swi6-Mbp1 MBF complex regulate Mcd1 levels to impact eco1 rad61 cell growth in Saccharomyces cerevisiaeSemantic proximity Read ↗

DNA double-strand breaks trigger genome-wide sister-chromatid cohesion through Eco1 (Ctf7).Semantic proximity Read ↗

Roberts syndrome is caused by mutations in ESCO2, a human homolog of yeast ECO1 that is essential for the establishment of sister chromatid cohesionSemantic proximity Read ↗

SID1-1: a mutation affecting meiotic sister-chromatid association in yeast.Semantic proximity Read ↗

The acetyltransferase Eco1 elicits cohesin dimerization during S phaseSemantic proximity Read ↗

Functional control of Eco1 through the MCM complex in sister chromatid cohesion.Semantic proximity Read ↗

Cdk1-dependent destruction of Eco1 prevents cohesion establishment after S phase.Semantic proximity Read ↗

DNA resection at chromosome breaks promotes genome stability by constraining non-allelic homologous recombination.Semantic proximity Read ↗

G1-Cyclin2 (Cln2) promotes chromosome hypercondensation in <i>eco1/ctf7 rad61</i> null cells during hyperthermic stress in <i>Saccharomyces cerevisiae</i>Semantic proximity Read ↗

A multi-step pathway for the establishment of sister chromatid cohesion.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.