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Article

A multi-step pathway for the establishment of sister chromatid cohesion.

PLoS genetics - 19 Jan 2007

Milutinovich Mark, Unal Elçin, Ward Chris, Skibbens Robert V, Koshland Douglas

Abstract excerpt

The cohesion of sister chromatids is mediated by cohesin, a protein complex containing members of the structural maintenance of chromosome (Smc) family. How cohesins tether sister chromatids is not yet understood. Here, we mutate SMC1, the gene encoding a cohesin subunit of budding yeast, by random insertion dominant negative mutagenesis to generate alleles that are highly informative for cohesin assembly and...

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Identifiers

PMID: 17238288
DOI: 10.1371/journal.pgen.0030012
PMCID: PMC1779304

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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