Article
Genotype-specific neutralization and protection by antibodies against dengue virus type 3.
Journal of virology - 1 Oct 2010
Brien James D, Austin S Kyle, Sukupolvi-Petty Soila, O'Brien Katie M, Johnson Syd, Fremont Daved H, Diamond Michael S
Abstract excerpt
Dengue viruses (DENV) comprise a family of related positive-strand RNA viruses that infect up to 100 million people annually. Currently, there is no approved vaccine or therapy to prevent infection or diminish disease severity. Protection against DENV is associated with the development of neutralizing antibodies that recognize the viral envelope (E) protein. Here, with the goal of identifying monoclonal...
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