Article
Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions.
Proceedings of the National Academy of Sciences of the United States of America - 8 May 2012
de Alwis Ruklanthi, Smith Scott A, Olivarez Nicholas P, Messer William B, Huynh Jeremy P, Wahala Wahala M P B, White Laura J, Diamond Michael S, Baric Ralph S, Crowe James E, de Silva Aravinda M
Abstract excerpt
Dengue is a mosquito-borne flavivirus that is spreading at an unprecedented rate and has developed into a major health and economic burden in over 50 countries. Even though infected individuals develop potent and long-lasting serotype-specific neutralizing antibodies (Abs), the epitopes engaged b...
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