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Article

Antibody recognition and neutralization determinants on domains I and II of West Nile Virus envelope protein.

Journal of virology - 1 Dec 2006

Oliphant Theodore, Nybakken Grant E, Engle Michael, Xu Qing, Nelson Christopher A, Sukupolvi-Petty Soila, Marri Anantha, Lachmi Bat-El, Olshevsky Udy, Fremont Daved H, Pierson Theodore C, Diamond Michael S

Abstract excerpt

Previous studies have demonstrated that monoclonal antibodies (MAbs) against an epitope on the lateral surface of domain III (DIII) of the West Nile virus (WNV) envelope (E) strongly protect against infection in animals. Herein, we observed significantly less efficient neutralization by 89 MAbs that recognized domain I (DI) or II (DII) of WNV E protein. Moreover, in cells expressing Fc gamma receptors, many of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17035317
DOI: 10.1128/JVI.01732-06
PMCID: PMC1676294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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