Article
Structure and Function Analysis of Therapeutic Monoclonal Antibodies against Dengue Virus Type 2
1 Jul 2010
Abstract excerpt
Dengue virus (DENV) is the most prevalent insect-transmitted viral disease in humans globally, and currently no specific therapy or vaccine is available. Protection against DENV and other related flaviviruses is associated with the development of antibodies against the viral envelope (E) protein. Although prior studies have characterized the neutralizing activity of monoclonal antibodies (MAbs) against DENV type...
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