Article
Natural strain variation and antibody neutralization of dengue serotype 3 viruses.
PLoS pathogens - 19 Mar 2010
Wahala Wahala M P B, Donaldson Eric F, de Alwis Ruklanthi, Accavitti-Loper Mary Ann, Baric Ralph S, de Silva Aravinda M
Abstract excerpt
Dengue viruses (DENVs) are emerging, mosquito-borne flaviviruses which cause dengue fever and dengue hemorrhagic fever. The DENV complex consists of 4 serotypes designated DENV1-DENV4. Following natural infection with DENV, individuals develop serotype specific, neutralizing antibody responses. Monoclonal antibodies (MAbs) have been used to map neutralizing epitopes on dengue and other flaviviruses. Most...
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