Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Associations between Certain Polymorphisms in Proinflammatory Cytokines and Predisposition of Alzheimer's Disease: A Meta-Analysis.

Dementia and geriatric cognitive disorders - 1 Jan 2021

Zhang Qin, Yang KongBin, Zhang ZhongLing, Zhang RuiHua

Abstract excerpt

BACKGROUND: Functional gene polymorphisms of proinflammatory cytokines such as tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), interleukin-8 (IL-8), and interleukin-18 (IL-18) may contribute to the onset and development of Alzheimer's disease (AD), but the relationships between these polymorphisms and predisposition of AD remain controversial. OBJECTIVES: This meta-analysis was conducted to more robustly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Asian People

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cytokines

Share to Interleukin-18

Share to Interleukin-6

Share to Interleukin-8

Share to Tumor Necrosis Factor-alpha

Share to White People

Source

Identifiers

PMID: 34404042
DOI: 10.1159/000508889

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Associations between Certain Polymorphisms in Proinflammatory Cytokines and Predisposition of Alzheimer's Disease: A Meta-Analysis.PMID 34404042Read ↗

IL-6, IL-8 and IL-10 polymorphisms may impact predisposition of Alzheimer's disease: a meta-analysis.Semantic proximity Read ↗

Association between interleukin-6 -174G/C polymorphism and the risk of Alzheimer's disease: a meta-analysis.Semantic proximity Read ↗

IL-1β, IL-6, IL-10, and TNFα Single Nucleotide Polymorphisms in Human Influence the Susceptibility to Alzheimer's Disease Pathology.Semantic proximity Read ↗

Interleukin-18 -137 G/C and -607 C/A polymorphisms and Alzheimer's disease risk: a meta-analysis.Semantic proximity Read ↗

IL-6-174 G/C and -572 C/G polymorphisms and risk of Alzheimer's disease.Semantic proximity Read ↗

Inflammatory Cytokines and Alzheimer's Disease: A Review from the Perspective of Genetic Polymorphisms.Semantic proximity Read ↗

Effect of Proinflammatory Gene Polymorphisms on the Risk of Alzheimer's DiseaseSemantic proximity Read ↗

The genetic association of IL-17A rs8193036 with the susceptibility to Alzheimer's disease.Semantic proximity Read ↗

Interleukin-6 -174G/C polymorphism and the risk of Alzheimer's disease in Caucasians: a meta-analysis.Semantic proximity Read ↗

Cytokine gene polymorphisms and serum cytokine levels identify a neuroinflammatory nexus in Alzheimer's disease.Semantic proximity Read ↗

Association between polymorphism in the promoter region of Interleukin 6 (-174 G/C) and risk of Alzheimer's disease: a meta-analysis.Semantic proximity Read ↗

Genetic polymorphisms of interleukin genes and the risk of Alzheimer's disease: An update meta-analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.